Inhalt des Dokuments
Dr. Markus Dahlem
- © TU Berlin
CV (detailed version, english) (PDF, 550,0 KB)
CV (short version, german)
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Research areas Nonlinear science, in particular, pattern formation in the brain
Rhythmic behavior in coupled excitable neurons
Migraine, stroke
Biomedical engineering
| Office: | Institut für Theoretische Physik Technische Universität Berlin Hardenbergstr. 36 D-10623 Berlin |
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| Email: | dahlem(at)itp.physik.tu-berlin.de |
Nonlinear science meets Neurology
- Migraine, stroke, and epilepsies are all related to cortical spreading depression.
- © Dahlem, TUB
I develop neural network models of a phenomen called cortical spreading depression (CSD) related to migraine, stroke, and epilepsies.
The main goal of my research is to understand cortical susceptibility to cortical spreading depression in terms of neural circuitry, and to use the knowledge to develop novel strategies in therapeutics.
Moreover, I collect data on multiple time and length scales, from electrocorticography (ECoG) to functional imaging (fMRI) to
(i) match this data against computer-assisted diagnostic reports of focal symptoms.
(ii) investigate both non-invasive (TMS and tDCS) and invasive (ECoG-based recurrent brain-computer interfaces) feedback strategies.
Stroke
- ECoG-based short-range recurrent functional stimulation techniques to stabilize tissue at risk of progressive damage
- © Copyright??
My research provides a unique set of data linking physiological and mathematical pictures of the cellular dynamics of neurological disorders and opens up new avenues for therapies.
Failing internal feedback control is, for example, suggested to be replaced by ECoG-based short-range recurrent functional stimulation that initiates the normal hyperperfusion haemodynamic response in a demand-controlled way and stabilizes the tissue at risk during the critical phase of CSD passage.