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B8: Dynamics and control of inter-areal brain networks

Principal investigator:

Prof. Dr. Klaus Obermayer [1]

Project summary:

We will study models of inter-areal brain networks whose topology is constrained by data from human imaging studies. Delay-coupled network nodes will be equipped with (1) simplified dynamical systems (Hopf normal forms & FitzHugh-Nagumo models) and (2) biophysically calibrated neural mass models both including noise. Dynamics will be controlled through coupling terms describing the influence of external electric fields on the neuronal dynamics. We will characterize the dynamical states of the network and will design feedback control schemes for stabilizing or switching between states. Results will shed light on the controllability of high-dimensional states in heterogeneous networks and will lead to a better understanding of the impact of non-invasive brain stimulation on global brain activity.

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